Winger Filipo Daugunu and robust Rob Valetini will start for the Wallabies in their second Test against Wales on Saturday in Melbourne.
Daugunu will be positioned on the left wing, while Valetini will serve as the blindside flanker.
Number 8 Langi Gleeson from the Waratahs has been included in the Match Day 23 and will be available as a reserve.
Prop James Slipper will assume the role of captain.
Slipper steps up as captain due to an injury to backrower Liam Wright, which has sidelined him.
This will mark the 15th occasion the 35-year-old Slipper has captained Australia, having recently set the record for the most caps for a front-rower.
In Wright’s absence, Slipper’s Brumbies teammate Charlie Cale will make his debut start at number eight.
Cale, one of seven debutants in last week’s victory, will push Valetini to the blindside flanker position, mimicking their Brumbies setup.
The starting side remains otherwise unchanged, with Coach Joe Schmidt making several alterations to the bench, highlighted by potential debutant Josh Nasser.
Nasser, son of former Wallaby Brendan, joins Isaac Kailea and Allan Alaalatoa as front-row replacements.
Gleeson is set for his first Wallabies appearance in 2024 alongside Angus Blyth.
Western Force duo Nic White and Ben Donaldson round out the bench, providing an experienced combination with Dylan Pietsch.
The Wallabies will don their First Nations jersey in honor of NAIDOC week, with the match kicking off at 9.45pm.
Wallabies (1-15): James Slipper (C), Matt Faessler, Taniela Tupou, Jeremy Williams, Lukhan Salakaia-Loto, Rob Valetini, Fraser McReight, Charlie Cale, Jake Gordon, Noah Lolesio, Filipo Daugunu, Hunter Paisami, Josh Flook, Andrew Kellaway, Tom Wright.
Reserves: Josh Nasser, Isaac Kailea, Allan Alaalatoa, Angus Blyth, Langi Gleeson, Nic White, Ben Donaldson, Dylan Pietsch.